Thermo Fisher Scientific Phospho-CAD (Thr456) Polyclonal Antibody
인간 CAD 단백질의 Thr456 인산화 부위를 인식하는 폴리클로날 항체입니다. IHC(P)에서 1:50~1:100 희석 비율로 사용 가능합니다. 친화 크로마토그래피로 정제되었으며, PBS와 50% 글리세롤에 보존됩니다. 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of threonine 456 (P-I-T(p)-P-H) derived from Human CAD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554111 |
Product Specific Information
- A suggested positive control for IHC is human colon carcinoma.
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase.
This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, indicating a direct link between MAPK activation and de novo pyrimidine nucleotide biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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