Thermo Fisher Scientific FMO5 Polyclonal Antibody
Thermo Fisher Scientific의 FMO5 Polyclonal Antibody는 인간 FMO5 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot 및 IHC(P)에서 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA530035
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–202 of Human FMO5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547509 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (87%), Rat (87%), Rabbit (89%), Bovine (93%), Guinea pig (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in humans, resulting in a subpopulation with reduced TMA N-oxidation capacity (Trimethylaminuria, fish odor syndrome).
Three forms of the enzyme—FMO1 (fetal liver), FMO2 (adult liver), and FMO3—are encoded by genes clustered in the 1q23–q25 region.
Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyze the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
Alternative splicing results in multiple transcript variants.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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