Thermo Fisher Scientific SQSTM1 Monoclonal Antibody (OTI4C8), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The SQSTM1 gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the NF-κB signaling pathway.
It acts as a scaffolding/adaptor protein with TNF receptor-associated factor 6 to mediate NF-κB activation.
Alternatively spliced transcript variants encoding identical or distinct isoforms have been identified.
Mutations in SQSTM1 are associated with sporadic and familial Paget disease of bone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.