Thermo Fisher Scientific Lass3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Lass3. Recombinant protein control fragment (Product #RP-89369). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Lass3,uniProtId:Q8IU89-1,ncbiNodeId:9606,antigenRange:59-120,antigenLength:383,antigenImageFileName:PA5-52250_Lass3_Q8IU89-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52250_Lass3_Q8IU89-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643296

Product Specific Information

Immunogen sequence: FVASPLAKSF GIKETVRKVT PNTVLENFFK HSTRQPLQTD IYGLAKKCNL TERQVERWFR SR

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 66%.

Target Information

LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.