
Thermo Fisher Scientific DAND5 Polyclonal Antibody
DAND5 단백질을 표적하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 합성 펩타이드 면역원 기반, Affinity Chromatography로 정제. 액상 형태로 -20°C 보관.
- 카탈로그번호
- PA545897
- 판매단위
- pk
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Thermo Fisher Scientific DAND5 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human DAND5 (aa 14–63) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606624 |
Product Specific Information
- Peptide sequence: SGALPTGSGR PEPQSPRPQS WAAANQTWAL GPGALPPLVP ASALGSWKAF
- Sequence homology: Human: 100%
Target Information
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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