Thermo Fisher Scientific Tafasitamab Humanized Recombinant Human Monoclonal Antibody
CD19을 표적으로 하는 인간화 재조합 단일클론 항체로, ELISA 등 다양한 연구용 분석에 적합. CHO 세포에서 발현되며 Protein A로 정제된 액상 형태. 낮은 엔도톡신 수준과 높은 순도 제공. 연구용으로만 사용 가능.
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Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa / IgG2, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human CD19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911187 |
Product Specific Information
- Endotoxin level: < 0.01 EU/µg (LAL method)
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Tafasitamab is a biosimilar that targets CD19.
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains and is expressed on 100% of peripheral B cells. It can also be found on certain myeloid leukemia cells, particularly those of monocytic lineage.
CD19 functions as a signal-amplifying coreceptor for the B cell receptor (BCR) and plays a central role in regulating normal and malignant B cell proliferation.
Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression causes B cell hyperactivity.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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