Thermo Fisher Scientific PRDX3 Monoclonal Antibody (2B11)
PRDX3 단백질을 인식하는 Thermo Fisher Scientific의 mouse monoclonal antibody(2B11). ELISA 및 IP에 사용 가능하며, HeLa 세포를 양성 대조군으로 권장. 미토콘드리아 내 Peroxiredoxin 3 연구에 적합한 고품질 연구용 항체.
- 판매단위
- pk
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Applications
ELISA (ELISA)
- Assay-dependent
Immunoprecipitation (IP)
- 2 µg
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B11 |
| Immunogen | Purified, recombinant, human peroxiredoxin 3 protein expressed in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2168364 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are associated with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), classified by amino acid sequence homology and active site cysteine residues, exhibit thiol-specific antioxidant activity across all kingdoms.
Mammalian Prx consists of six members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx types. Except Prx VI (1-Cys subgroup), the other five 2-Cys Prx isotypes possess thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system.
Mammalian Prxs are 20–30 kDa in size and show distinct subcellular localization:
- Prx I, II, and VI: cytosol
- Prx III: mitochondria
- Prx IV: endoplasmic reticulum and secretion
- Prx V: peroxisome, mitochondria, and cytosol
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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