Thermo Fisher Scientific PIK3CG Monoclonal Antibody (4B5D2)
PIK3CG 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 ELISA에 적합. 인간 시료에 반응하며, Protein G로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B5D2 |
| Immunogen | Purified recombinant fragment of human PIK3CG (aa 1–100) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898507 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. Unlike the class IA enzymes that signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs. It phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring and modulates extracellular signals, including those from E-cadherin-mediated cell-cell adhesion. This plays a key role in maintaining epithelial structural integrity and regulating NK cell cytotoxicity. The gene is located in a commonly deleted region of chromosome 7 associated with myeloid leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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