Thermo Fisher Scientific BRSK1 Polyclonal Antibody
Human 및 Mouse 시료에서 BRSK1 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 액상 형태로 1 mg/mL 농도 제공. Affinity chromatography로 정제되어 높은 특이성과 재현성을 보장.
- 카탈로그번호
- PA5101216
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BRSK1 (Accession Q8TDC3), corresponding to amino acid residues Y352–V402 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850657 |
Product Specific Information
Antibody detects endogenous levels of total BRSK1.
Target Information
BRSK1 (SAD1) is a serine/threonine kinase and a UV-induced DNA damage checkpoint kinase. It is ubiquitously expressed, with highest levels in the brain and testes. BRSK1 is involved in stress-induced cell cycle arrest and plays a role in DNA damage checkpoint function. Both BRSK1 and BRSK2 are required for mammalian neuronal polarization. Double-mutant mice lacking both proteins die shortly after birth, and their neurons show abnormal neurite morphology with mixed axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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