Thermo Fisher Scientific TET1 Recombinant Rabbit Monoclonal Antibody (10S0X1)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

10S0X1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1749-1902 of mouse Tet1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TET1,uniProtId:Q3URK3-1,ncbiNodeId:10090,antigenRange:1749-1902,antigenLength:2039,antigenImageFileName:MA5-55570_TET1_Q3URK3-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55570_TET1_Q3URK3-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: HNTKSFSSAS STSHLVKDES TDFCPLQASS AETSTCTYSK TASGGFAETS SILHCTMPSG AHSGANAAAG ECTGTVQPAE VAAHPHQSLP TADSPVHAEP LTSPSEQLTS NQSNQQLPLL SNSQKLASCQ VEDERHPEAD EPQHPEDDNL PQLD

Target Information

Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.