Thermo Fisher Scientific SLC34A1 Polyclonal Antibody
SLC34A1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ELISA에 적합하며 인간, 생쥐, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 안정적인 PBS/glycerol 버퍼 제공.
- 카탈로그번호
- PA5120232
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 562–639 of human SLC34A1 (NP_0030433) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913804 |
Product Specific Information
- Positive test controls: 293T, A-549, U-87MG, Mouse kidney, Rat lung
- Target localization: Membrane, Multi-pass membrane protein
- Immunogen sequence:
QSRSPGHLPK WLQTWDFLPR WMHSLKPLDH LITRATLCCA RPEPRSPPLP PRVFLEELPP ATPSPRLALP AHHNATRL
Target Information
Renal tubular reabsorption of phosphate is critical to maintaining phosphate homeostasis in mammals. The brush-border membrane Na⁺/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na⁺/Pi cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells. NPT2 gene expression is crucial for PTH effects on renal phosphate handling. However, renal expression of the sodium/phosphate cotransporter gene NPT2 is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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