Thermo Fisher Scientific RNF14 Polyclonal Antibody
RNF14 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human과 Mouse 반응성을 가지며, 고순도 항원 친화 크로마토그래피로 정제된 액상 제품입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the N-terminal of human ring finger protein 14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636325 |
Product Specific Information
This antibody detects endogenous levels of total RNF14 protein.
Target Information
The protein encoded by this gene contains a RING zinc finger motif involved in protein-protein interactions. It interacts with the androgen receptor (AR) and may function as a coactivator inducing AR target gene expression in the prostate. A dominant negative mutant has been shown to inhibit AR-mediated prostate cancer growth. The protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) for certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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