Thermo Fisher Scientific RIN1 Polyclonal Antibody
Thermo Fisher Scientific의 RIN1 Polyclonal Antibody는 인간, 생쥐, 랫트 시료에서 RIN1 단백질을 검출하는 토끼 유래 IgG 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관 가능합니다.
- 카탈로그번호
- PA550107
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human RIN1 (UniProt ID: Q13671-1, antigen range: 665–690) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635560 |
Product Specific Information
This antibody detects endogenous levels of total RIN1 protein.
Target Information
Rit and its neuron-specific homologue, Rin, define a subfamily of Ras-related GTPases. These proteins are membrane-associated despite lacking a CAAX box or similar C-terminal lipidation motif. Rit and Rin share 64% amino acid sequence identity and a conserved nine amino acid effector domain (DPTIEDAYK) between murine and human proteins. Although similar to Ras, Rit and Rin interact with Ras-binding proteins such as RalGDS, Rlf, and AF-6, but not with Raf kinases, RIN1, or the p110 subunit of PI3 kinase. They may play roles in signaling pathways distinct from those controlled by Ras.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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