Thermo Fisher Scientific KIRREL3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1 µg/mL
• Publications: -

Product Specifications

Product Specific Information

• In direct ELISAs, less than 3% cross-reactivity with recombinant human Kirrel1 and Kirrel2 is observed.
• Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration.
This gene encodes a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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