Thermo Fisher Scientific KIRREL3 Polyclonal Antibody
KIRREL3 단백질을 인식하는 Sheep 유래 Polyclonal Antibody로 인간, 마우스, 랫트 반응성. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. Lyophilized 형태로 보존, -20°C에서 보관 권장. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Kirrel3/NEPH2 (Tyr33–Ala535) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606766 |
Product Specific Information
- In direct ELISAs, less than 3% cross-reactivity with recombinant human Kirrel1 and Kirrel2 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration.
This gene encodes a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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