Thermo Fisher Scientific MAFA Polyclonal Antibody
MAFA 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 항체로 인간 및 마우스 반응성. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 0.5 mg/mL 농도. 장기 보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific MAFA Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human MAFA (aa 110–159) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884370 |
Product Specific Information
- Immunogen sequence:
KPALEDLYWM SGYQHHLNPE ALNLTPEDAV EALIGSGHHG AHHGAHHPAA - Storage guidance:
- Short term: Store at 2–8°C up to 1 week
- Long term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
Cow: 100%; Dog: 79%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 83%
Target Information
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. It can act as either an oncogene or tumor suppressor depending on cellular context.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: PA5-113855_MAFA_Q8NHW3-1_Rabbit.svg, PA5-113855_MAFA_Q8NHW3-1_Rabbit_PDP.jpeg)
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