Thermo Fisher Scientific MAFA Polyclonal Antibody

Thermo Fisher Scientific MAFA Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  KPALEDLYWM SGYQHHLNPE ALNLTPEDAV EALIGSGHHG AHHGAHHPAA
• Storage guidance:
  • Short term: Store at 2–8°C up to 1 week
  • Long term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 100%; Dog: 79%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 83%

Target Information

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. It can act as either an oncogene or tumor suppressor depending on cellular context.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지

(이미지: PA5-113855_MAFA_Q8NHW3-1_Rabbit.svg, PA5-113855_MAFA_Q8NHW3-1_Rabbit_PDP.jpeg)