Thermo Fisher Scientific FOXR1 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  KKPNPDKDGP DYEPNLWMWV NPNIVYPPGK LEVSGRRKRE DLTSTLPSSQ

• Storage guidance:
  For short-term use, store at 2–8°C up to 1 week.
  For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Predicted homology:
  Guinea Pig: 100%
  Human: 100%
  Mouse: 100%
  Rat: 100%

Target Information

The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 amino acids. FOX transcription factors play roles in determining cell fate during early development.

FOXR1 (forkhead box protein R1), also known as FOXN5 or DLNB13, is a 292 amino acid nuclear protein that belongs to the FOX family and contains one forkhead DNA-binding domain. Through chromosomal aberrations such as retroviral integration, gene amplification, or translocation, FOXR1 may be involved in the development of certain invasive carcinomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.