Thermo Fisher Scientific GLP-2 Polyclonal Antibody
GLP-2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며 Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human GLP-2, amino acids 146–178 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Glucagon is a 29-residue polypeptide hormone (MW 3482) produced in the pancreas. A related hormone, enteroglucagon (or oxyntomodulin), produced in the mucosa of the small and large intestine, consists of the 29 amino acid sequence of pancreatic glucagon extended by 8 additional residues at the C-terminus.
The biological activities of pancreatic glucagon include glycogenolysis, lipolysis, gluconeogenesis, and ketogenesis, which are antagonistic to insulin action, leading to increased blood glucose levels.
Immunocytochemical studies have shown glucagon presence inside A or alpha cells, constituting 15–20% of the islet cell population, located at the periphery of human pancreatic islets. Pathological manifestations of glucagon-type peptides are mostly associated with tumors or glucagonomas.
Glucagon-specific antibodies are useful as cell and tumor markers in immunohistochemistry and as analytical tools for hormone quantification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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