Thermo Fisher Scientific Synaptotagmin Polyclonal Antibody
Synaptotagmin 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간, 마우스, 랫트 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 고품질 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Synaptotagmin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that regulate both exocytosis and endocytosis, playing a key role in neurotransmitter secretion. Calcium binding to Synaptotagmin I triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1, influencing calcium-dependent interactions. Synaptotagmin III participates in calcium-dependent exocytosis in endocrine cells and neurons, while Synaptotagmin IV is highly expressed in neuronal tissues, particularly in the hippocampus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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