Thermo Fisher Scientific HSP60 Polyclonal Antibody
HSP60 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 ICC/IF에 사용 가능. 인간에 반응하며, 서열 상 유사성으로 다른 종에도 예측 반응. 1.5 mg/mL 농도의 액상 형태로 제공되며, PBS buffer 및 sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 187–215 from the central region of human HSPD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2233124 |
Product Specific Information
This antibody is predicted to react with bovine, chicken, hamster, mouse, and rat based on sequence homology.
Target Information
The HSPD1 gene encodes a member of the chaperonin family. The encoded mitochondrial protein functions as a signaling molecule in the innate immune system and is essential for the folding and assembly of newly imported mitochondrial proteins. The gene is adjacent to a related family member, with a bidirectional promoter region between them. Several pseudogenes are associated with this gene. Two transcript variants encoding the same protein have been identified. Mutations in this gene are linked to autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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