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Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody, Biotin
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Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody, Biotin

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Pannexin 1 단백질을 인식하는 Biotin 결합 토끼 폴리클로날 항체. Western blot, ELISA, IP에 적합. 고순도 친화 크로마토그래피 정제. 인간 시료 반응성. 연구용으로만 사용 가능.

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pk
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Thermo Fisher Scientific PANX1-BIOTIN Pannexin 1 Polyclonal Antibody, Biotin 200 ul pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody, Biotin

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:500–1:1,000
ELISA 1:10,000
Immunoprecipitation (IP) 1:50–1:250

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide taken within amino acid region from human Pannexin 1 protein
Conjugate Biotin
Form Liquid
Concentration 0.5–1.5 mg/mL
Purification Affinity chromatography
Storage Buffer Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

The pannexin gene family encodes a second class of putative gap junction proteins that are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is more distantly related. PANX1 forms a mechanosensitive ATP-permeable channel between adjacent cells and within the endoplasmic reticulum. It may function as a Ca²⁺ leak channel to regulate ER Ca²⁺ homeostasis and influence neural stem and progenitor cell proliferation.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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