Thermo Fisher Scientific EPS8L1 Polyclonal Antibody
EPS8L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB에 1:500~1:1,000 희석비로 사용 가능. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로 세포 성장 및 세포골격 연구에 적합.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 414–458 of Human EPS8L1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719706 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >96% as determined by SDS-PAGE.
Target Information
Eps8L1 (EPS8-like 1), also known as DRC3 or EPS8R1, is a 723 amino acid cytoplasmic protein belonging to the Eps8 (epidermal growth factor receptor pathway substrate 8) family. It is expressed in placental tissue and stimulates the guanine exchange activity of Sos1, which promotes the exchange of Ras-bound GDP for GTP. Eps8L1 associates with Actin and may play a role in membrane ruffling and remodeling of the Actin cytoskeleton. Through regulation of protein activation and cytoskeleton dynamics, Eps8L1 may participate in cell growth and differentiation. It contains one SH3 domain and is expressed as four isoforms due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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