Thermo Fisher Scientific Atg16L1 Polyclonal Antibody
ATG16L1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성이 높고, 액상 형태로 4°C에서 보관.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and 350 of human ATG16 Autophagy Related 16-like 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
Autophagy related protein 16 L (ATG16L) is encoded by the ATG16L gene located on chromosome 2 in humans. Also known as WD30 or IBD10 (Inflammatory Bowel Disease 10).
ATG12 and ATG5 conjugate and oligomerize with ATG16L to form an 800 kDa complex, the Atg16L complex, which facilitates coupling of LC3 to phosphatidylethanolamine (PE). This ubiquitin-like conjugation system is a widely used marker for autophagy. The ATG16L complex, along with ATG18 and ATG21, prevents premature cleavage of ATG8-PE by the cysteine protease Atg4 until autophagosome completion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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