Thermo Fisher Scientific NTPCR Polyclonal Antibody

Applications

• Western Blot (WB): 1:2,000–1:10,000

Product Specifications

Product Specific Information

• The recommended shelf life for this product is 1 year from date of receipt.

Target Information

C1orf57, also known as nucleoside triphosphate phosphohydrolase, belongs to the THEP1 NTPase family. It and its mouse homolog (2310079N02Rik) are 190 amino acid proteins exhibiting nucleotide phosphatase activity toward ATP, GTP, TTP, CTP, and UTP. Acting as a monomer, it hydrolyzes nucleoside diphosphates with lower efficiency.

The gene encoding C1orf57 maps to human chromosome 1, the largest human chromosome (approximately 260 million base pairs, ~8% of the human genome). Chromosome 1 contains about 3,000 genes, many of which are associated with genetic diseases such as Hutchinson-Gilford progeria (LMNA gene), familial adenomatous polyposis (MUTYH gene), Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.