Thermo Fisher Scientific PDGFRB Recombinant Rabbit Monoclonal Antibody (ARC0009)
PDGFRB 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체 ARC0009. Western blot, ICC/IF, ELISA에 적합하며, 인간·마우스·랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장 가능.
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- MA535288
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0009 |
| Immunogen | Synthetic peptide corresponding to amino acids 1000–1106 of human PDGFRB (P09619) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849190 |
Product Specific Information
Immunogen sequence:
SPLDTSSVLY TAVQPNEGDN DYIIPLPDPK PEVADEGPLE GSPSLASSTL NEVNTSSTIS CDSPLEPQDE PEPEPQLELQ VEPEPELEQL PDSGCPAPRA EAEDSFL
Target Information
PDGFRB (CD140b) is a receptor tyrosine kinase involved in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for mesenchymal-origin cells. The receptor can form homodimers or heterodimers with PDGFRA depending on the bound ligand. The PDGFRB gene, located on chromosome 5, is adjacent to GM-CSF and CSF1R genes, which may be associated with 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB to ETV6 can lead to chronic myeloproliferative disorders with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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