Thermo Fisher Scientific PAK6 Polyclonal Antibody
Thermo Fisher Scientific의 PAK6 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 토끼 IgG 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 고순도(>95%)로 정제되었으며, PAK6 단백질 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human PAK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2803789 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
PAK6 is a serine/threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors. The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac.
PAKs are divided into two groups:
- Group 1 (PAK1, 2, 3): Activated by Cdc42/Rac binding and involved in gene transcription, apoptosis, and cell morphology/motility.
- Group 2 (PAK4, 5, 6): Not activated by Cdc42/Rac binding. PAK6 may be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting its role in stress-related cellular responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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