Thermo Fisher Scientific Caspase 2 Recombinant Rabbit Monoclonal Antibody (3D4)
Caspase-2 단백질을 인식하는 토끼 단클론 항체로, Western blot과 IHC(P)에서 검증됨. HEK293 세포에서 발현된 재조합 항체이며, 높은 특이성과 재현성을 제공. 세포자멸사 연구용으로 적합하며, -20°C 이하에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3D4 |
| Immunogen | A synthesized peptide derived from human Caspase-2 (amino acids 334–393, UniProt ID: P42575-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898286 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Caspase 2 gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce large and small subunits, which dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by various apoptotic stimuli. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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