
Thermo Fisher Scientific MMS21 Polyclonal Antibody
MMS21 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며 4°C에서 보관. 연구용 한정 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 197 to 247 of human Non-SMC Element 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes the large subunit of DNA damage-binding protein, which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Defective activity of this protein causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE). Mutation analysis is required to confirm whether the defect in XPE patients is in this gene or in the gene encoding the small subunit. Additionally, Best vitelliform macular dystrophy is mapped to the same region as this gene on 11q, but no sequence alterations of this gene are demonstrated in Best disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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