Thermo Fisher Scientific Phospho-PKC mu (Ser910) Polyclonal Antibody
PKC mu (Ser910) 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 PKD1/PKC mu 유래 합성 인산화 펩타이드로 면역화되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human PKD1/PKC mu around the phosphorylation site of Ser910 (R-V-SP-I-L) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554989 |
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways.
In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity.
PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent.
PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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