Thermo Fisher Scientific GSR Polyclonal Antibody
Thermo Fisher Scientific의 GSR Polyclonal Antibody는 인간, 생쥐, 제브라피쉬 등 다양한 종에서 반응하는 항체로, Western blot 및 IHC에 사용됩니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 안정적인 저장이 가능합니다.
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Applications
- Western Blot (WB): 0.2–1.0 µg/mL
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human GSR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688581 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% | Dog: 93% | Guinea Pig: 100% | Horse: 86% | Human: 100% | Mouse: 100% | Rabbit: 100% | Rat: 93%
Target Information
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The enzyme is a homodimeric flavoprotein central to cellular antioxidant defense. It reduces oxidized glutathione disulfide (GSSG) to glutathione (GSH), a key cellular antioxidant.
Rare mutations in this gene cause hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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