Thermo Fisher Scientific PSMA5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PSMA5 for use in WB, IHC, and IP applications. Recognizes proteasome 20S core alpha subunit involved in peptide cleavage. Supplied as liquid, unconjugated form. For research use only.
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Thermo Fisher Scientific PSMA5 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10,000–1:25,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human PSMA5 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902803 |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure comprises four rings of 28 non-identical subunits; two rings consist of seven alpha subunits, and two rings consist of seven beta subunits. Proteasomes are distributed throughout eukaryotic cells at high concentrations and cleave peptides in an ATP/ubiquitin-dependent process through a non-lysosomal pathway. A modified form, the immunoproteasome, plays an essential role in processing class I MHC peptides. The PSMA5 gene encodes a member of the peptidase T1A family, which serves as a 20S core alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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