Thermo Fisher Scientific Phospho-HRH1 (Ser398) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phosphorylated HRH1 (Ser398). Validated for ICC/IF applications. Suitable for human samples. Supplied as liquid at 1 mg/mL in PBS with 50% glycerol. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:200
- Suggested positive control: HUVEC cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine 398 (S-H-S(p)-R-Q) derived from Human Histamine H1 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554205 |
Product Specific Information
A suggested positive control for ICC/IF is HUVEC cells.
Target Information
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3, and H4. The HRH1 gene encodes an integral membrane protein belonging to the G protein-coupled receptor superfamily. It mediates smooth muscle contraction, increases capillary permeability, promotes catecholamine release from the adrenal medulla, and participates in neurotransmission in the central nervous system. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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