Thermo Fisher Scientific PRMT5 Polyclonal Antibody
PRMT5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, IP, ChIP 등 다양한 응용에 사용 가능. 인간 반응성 확인, 여러 종에서 높은 예측 반응성. 고순도 항원 친화 크로마토그래피 정제, 안정적 액상 형태로 제공.
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Thermo Fisher Scientific PRMT5 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Immunoprecipitation (IP) | 1:100–1:500 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PRMT5 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.31 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736458 |
Product Specific Information
- Positive Control: 293T, A431, Jurkat, Raji
- Predicted Reactivity: Mouse (98%), Rat (97%), Pig (98%), Rhesus Monkey (93%), Chimpanzee (99%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that catalyzes the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for MMA formation.
PRMT5 mediates symmetrical dimethylation of arginine residues in small nuclear ribonucleoproteins Sm D1 and Sm D3, essential for snRNP core particle assembly and biogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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