Thermo Fisher Scientific MCM2 Monoclonal Antibody (OTI3B12), TrueMAB
MCM2 단백질을 인식하는 Mouse monoclonal antibody. Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. DNA 복제 조절 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B12 |
| Immunogen | Full length human recombinant protein of human MCM2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication.
MCM2 (also known as CDCL1, mitotin, and BM28) is a human nuclear protein crucial for the cell cycle, participating in the initiation of DNA replication and cell division.
It is related to early S-phase proteins and has been mapped to chromosome 3q21.
Due to its localization, CDCL1 has been considered a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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