Thermo Fisher Scientific DNAJB4 Monoclonal Antibody (OTI2F8), TrueMAB

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI2F8

Immunogen

Human recombinant protein fragment corresponding to amino acids 2-337 of human DNAJB4 produced in E.coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DNAJB4,uniProtId:Q9UDY4-1,ncbiNodeId:9606,antigenRange:2-337,antigenLength:337,antigenImageFileName:TA812139_DNAJB4_Q9UDY4-1_House_mouse.svg,antigenImageFileNamePDP:TA812139_DNAJB4_Q9UDY4-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB4 (DnaJ homolog subfamily B member 4), also known as HLJ1, is expressed in skeletal muscle, heart and pancreas, and lower expression in brain, placenta and liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.