Thermo Fisher Scientific LILRB3 Monoclonal Antibody (OTI3G9), TrueMAB
인간 LILRB3 단백질(aa 465-631)에 특이적인 Mouse IgG1 단클론 항체. Western blot 검증 완료. 1 mg/mL 액상 형태, PBS/BSA/glycerol 버퍼에 보관. 연구용 전용으로 면역 반응 조절 관련 연구에 적합.
- 카탈로그번호
- TA812163
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution
- 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 465–631 of human LILRB3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells, binds to MHC class I molecules on antigen-presenting cells, and transduces a negative signal that inhibits stimulation of an immune response. It helps control inflammatory responses and cytotoxicity to focus immune reactions and limit autoreactivity. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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