Thermo Fisher Scientific Human Cripto Synthetic Peptide
인간 TDGF1 아미노 말단 17개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-34476과 함께 차단 펩타이드로 사용 가능. 액상 형태, 1 mg/mL 농도, PBS(pH 7.2) + 0.1% BSA 저장. 인간 Cripto(Nodal signaling 관련) 연구용.
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Thermo Fisher Scientific Human Cripto Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human TDGF1.
PEP-1518 can be used as a blocking peptide with polyclonal antibody PA5-34476.
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane protein involved in Nodal signaling.
Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells.
TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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