Thermo Fisher Scientific Human Pannexin 1 Synthetic Peptide
인간 Pannexin 1 단백질의 N-말단 17개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-34475의 차단 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며, PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1517
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human PANX1.
PEP-1517 can be used as a blocking peptide with polyclonal antibody PA5-34475.
Target Information
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca²⁺-leak channel to regulate ER Ca²⁺ homeostasis and regulates neural stem and progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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