Thermo Fisher Scientific RASSF8 Monoclonal Antibody (OTI2B6), TrueMAB
RASSF8 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western Blot과 IHC(P)에서 검증됨. Human에 반응하며, Lyophilized 형태로 제공. 종양 억제 단백질 연구 및 세포 접합 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Full length human recombinant protein of human RASSF8 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins.
This gene is essential for maintaining adherens junction function in epithelial cells and plays a role in epithelial cell migration.
It is considered a candidate lung tumor suppressor gene.
A chromosomal translocation t(12;22)(p11.2;q13.3) resulting in fusion with the FBLN1 gene is associated with complex synpolydactyly.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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