Thermo Fisher Scientific HBG2 Polyclonal Antibody
Thermo Fisher Scientific의 HBG2 폴리클로날 항체는 인간 Hemoglobin gamma G 단백질을 인식하며 Western blot에 적합합니다. Rabbit IgG 형식으로 항원 친화 크로마토그래피로 정제되었고, 고농도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human Hemoglobin gamma G Recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546482 |
Product Specific Information
- Recommended positive controls: U87-MG
- Predicted reactivity: Rhesus Monkey (97%), Chimpanzee (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen, and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF), which is normally replaced by adult hemoglobin (HbA) at birth.
In some beta-thalassemias and related conditions, gamma chain production continues into adulthood.
The two types of gamma chains differ at residue 136, where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth.
The order of the genes in the beta-globin cluster is: 5’-epsilon -- gamma-G -- gamma-A -- delta -- beta--3’.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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