Thermo Fisher Scientific Adipophilin/Perilipin-2 Monoclonal Antibody (ADFP, 1365)
인간 Adipophilin(Perilipin-2, ADFP)을 인식하는 마우스 단클론 항체로, Western blot, Flow cytometry, Peptide array 등에 사용 가능. 비결합형 액상 형태이며 Protein A/G로 정제됨. 지방 축적 세포 및 관련 질환 연구에 적합.
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Applications
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ADFP, 1365 |
| Immunogen | Recombinant fragment (around aa 249–376) of human Adipophilin (ADFP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Milk lipid globules from humans, cows, and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex containing butyrophilin and xanthine oxidase.
ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial, and epithelial cells. In tissues, expression of adipophilin is restricted to specific cell types such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis.
ADFP may serve as a marker for identifying specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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