Thermo Fisher Scientific Adipophilin/Perilipin-2 Monoclonal Antibody (ADFP, 1365)
인간 Adipophilin(Perilipin-2)을 인식하는 Mouse 단클론 항체로 Western blot, Flow cytometry, Peptide array 등에 사용 가능. PBS 기반 액상 형태, 보존제 무첨가. 지방 축적 세포 연구 및 분화 표지자 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ADFP, 1365 |
| Immunogen | Recombinant fragment (around aa 249–376) of human Adipophilin (ADFP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Antibody is tested in direct ELISA.
Target Information
Milk lipid globules from humans, cows, and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase.
ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial, and epithelial cells. In tissues, expression of adipophilin is restricted to specific cell types such as:
- Lactating mammary epithelial cells
- Adrenal cortex cells
- Sertoli and Leydig cells of the male reproductive system
- Steatosis or fatty change hepatocytes in alcoholic liver cirrhosis
ADFP may serve as a marker for specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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