Thermo Fisher Scientific NUAK2 Polyclonal Antibody
NUAK2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot, IHC, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NUAK2: 31–130 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719642 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as verified by SDS-PAGE.
Target Information
NUAK2 (also known as SNF1/AMP kinase-related kinase, SNARK) is a member of the NUAK family of SNF1-like kinase 2. NUAK2 is activated by muscle contraction and mediates contraction-stimulated glucose transport in skeletal muscle. It plays a role in cellular stress responses associated with obesity and type 2 diabetes. NUAK2 exhibits kinase activity against synthetic peptides, and its activity in keratinocytes is increased by AMP and AICAR, suggesting activation via an AMPK-dependent pathway. Glucose deprivation also increases NUAK2 activity in baby hamster kidney fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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