Thermo Fisher Scientific ZC3H13 Polyclonal Antibody
Human ZC3H13 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 40% 글리세롤 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZC3H13. Recombinant protein control fragment (Product #RP-97944). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649801 |
Product Specific Information
Immunogen sequence:
PSPRGKGYSS NYRRSPERPT GDLRERMKNK RQDVDTEPQK RNTEESSSPV RKESSRGRHR EKEDIKITKE RTPESEEENV EWETNRDDSD NGDINYDYVH ELSLEMKRQK I
Sequence identity:
- Mouse: 95%
- Rat: 96%
Target Information
The zinc finger CCCH domain-containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1-type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exist due to alternative splicing. The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include BRCA2 and RB1. Polysomy or trisomy of chromosome 13 is deleterious and associated with Patau syndrome, causing severe developmental and neurological defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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