Thermo Fisher Scientific IDH1 Monoclonal Antibody (OTI24A2), TrueMAB
IDH1 (mutant R132H)에 특이적인 Mouse Monoclonal Antibody. ELISA 및 Luminex 분석에 적합하며, 0.5 mg/mL 농도의 액상 형태로 제공. 친화 크로마토그래피로 정제되었고, PBS 버퍼에 보존되어 안정적인 연구용 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:100–1:1,000
Luminex (LUM)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI24A2 |
| Immunogen | Synthetic peptide around the R132 region of the human IDH conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Additional Formats
Target Information
Isocitrate dehydrogenases such as IDH1 catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizing NAD(+) and the other NADP(+).
Five isocitrate dehydrogenases have been reported — three NAD(+)-dependent (mitochondrial) and two NADP(+)-dependent (one mitochondrial, one cytosolic).
The cytoplasmic NADP(+)-dependent isozyme encoded by this gene is found in the cytoplasm and peroxisomes, containing a PTS-1 peroxisomal targeting signal.
It contributes to NADPH regeneration for peroxisomal reductions and cytoplasmic NADPH production.
This antibody product is specific for IDH1 (mutant R132H).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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