Thermo Fisher Scientific Phospho-NFkB p50/p105 (Ser903) Polyclonal Antibody
NFkB p50/p105의 Ser903 인산화 부위를 인식하는 rabbit polyclonal antibody. Western blot 및 면역세포염색(ICC/IF)에 적합. 액상 형태, 1 mg/mL 농도. 세포 성장 및 염증 조절 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NF-kB p105 around the phosphorylation site of Ser903 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903104 |
Target Information
NF-kB is a nuclear transcription factor activated by various extracellular and intracellular stimuli such as cytokines, UV radiation, stress, injury, and bacterial or viral products.
It regulates cellular processes including growth, differentiation, proliferation, apoptosis, and inflammation.
NFKB1 (p50) is a 50 kDa functional subunit of NF-kB, synthesized as a p105 precursor containing an N-terminal conserved RHD-region with nuclear localization, DNA-binding, and dimerization domains.
NFKB1 (p50) forms homodimers or heterodimers with p65 to create the functional NF-kB complex, directing its nuclear translocation and DNA-binding activity.
NF-kB has been implicated in pathological conditions such as AIDS, hematogenic cancer cell metastasis, and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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