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Thermo Fisher Scientific HECW1 Polyclonal Antibody
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Thermo Fisher Scientific HECW1 Polyclonal Antibody

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Human HECW1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고품질 시약. 0.1 mg/mL 농도의 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.

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pk
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마지막 업데이트 2025. 08. 03. 오후 01:22
Thermo Fisher Scientific PA552457 HECW1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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773,300원VAT 포함 850,630원

Thermo Fisher Scientific · Thermo Fisher Scientific HECW1 Polyclonal Antibody

Applications

  • Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50 dilution

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human HECW1 (UniProt ID: Q76N89-1, Range: 356–481)
Conjugate Unconjugated
Form Liquid
Concentration 0.1 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage Conditions Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles
Shipping Conditions Wet ice
RRID AB_2642373

Product Specific Information

Immunogen sequence:
STEPESAQIQ DSPMNNLMES GSGEPRSEAP ESSESWKPEQ LGEGSVPDGP GNQSIELSRP AEEAAVITEA GDQGMVSVGP EGAGELLAQV QKDIQPAPSA EELAEQLDLG EEASALLLED GEAPAS

  • Highest antigen sequence identity to the following orthologs:
    • Mouse: 45%
    • Rat: 44%

Target Information

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(PA5-52457_HECW1_Q76N89-1_Rabbit.svg 및 PA5-52457_HECW1_Q76N89-1_Rabbit_PDP.jpeg)

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