
Thermo Fisher Scientific HECW1 Polyclonal Antibody
Human HECW1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고품질 시약. 0.1 mg/mL 농도의 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HECW1 (UniProt ID: Q76N89-1, Range: 356–481) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2642373 |
Product Specific Information
Immunogen sequence:
STEPESAQIQ DSPMNNLMES GSGEPRSEAP ESSESWKPEQ LGEGSVPDGP GNQSIELSRP AEEAAVITEA GDQGMVSVGP EGAGELLAQV QKDIQPAPSA EELAEQLDLG EEASALLLED GEAPAS
- Highest antigen sequence identity to the following orthologs:
- Mouse: 45%
- Rat: 44%
Target Information
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-52457_HECW1_Q76N89-1_Rabbit.svg 및 PA5-52457_HECW1_Q76N89-1_Rabbit_PDP.jpeg)
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