Thermo Fisher Scientific ARHE Polyclonal Antibody
Human RND3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 보존제가 포함되지 않아 필요 시 sodium azide 첨가를 권장합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human RND3 (UniProt ID: P61587-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788476 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human RND3.
Target Information
Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors.
Like Ras, Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form.
Three major regulators of Rho activity have been identified:
- RhoGDIs – interact with GDP-bound Rho proteins to keep them in a resting complex
- GEFs – promote GDP/GTP exchange leading to activation of Rho proteins
- GAPs – stimulate GTP hydrolysis and return the activated Rho protein to its inactive form
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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