Thermo Fisher Scientific Phospho-SP1 (Thr278) Polyclonal Antibody
인간 SP1 단백질의 Thr278 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot과 Immunocytochemistry에 최적화. 1 mg/mL 액상 형태, -20°C 보관. 세포 성장 및 전사 조절 연구용으로 적합.
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Applications
Western Blot (WB)
Immunocytochemistry (ICC/IF)
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SP1 around the phosphorylation site of Thr278 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903216 |
Target Information
SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli.
Binds with high affinity to GC-rich motifs and regulates the expression of numerous genes involved in cell growth, apoptosis, differentiation, and immune responses.
Highly regulated by post-translational modifications including phosphorylation, sumoylation, proteolytic cleavage, glycosylation, and acetylation.
Also binds the PDGFR-alpha G-box promoter and may play a role in modulating cellular response to DNA damage.
Implicated in chromatin remodeling and recruitment of SMARCA4/BRG1 on the c-FOS promoter.
Plays an essential role in regulation of FE65 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-118716_SP1_P08047-1_Rabbit.svg, PA5-118716_SP1_P08047-1_Rabbit_PDP.jpeg)
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