Thermo Fisher Scientific PON1 Monoclonal Antibody (OTI2A6), TrueMAB
PON1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 ELISA 및 Luminex 분석에 적합. 비접합(Unconjugated) 형태이며, 고순도의 친화 크로마토그래피 정제 제품. 인간 시료 반응성, 안정한 PBS 버퍼에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- TA600113
- 판매단위
- pk
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Applications
ELISA (ELISA)
- Tested Dilution: 1:100–1:1,000
Luminex (LUM)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Full length human recombinant protein of human HPGD produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Additional Formats
Target Information
The paraoxonase (PON) gene family in humans includes three members: PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is primarily synthesized in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism has been implicated in neurodegeneration and may serve as an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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