Thermo Fisher Scientific TRAF2 Polyclonal Antibody
TRAF2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, IP에 적합합니다. 인간, 마우스, 비인간 영장류 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 비보존제 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding cysteine 192 of human TRAF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 25 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11001608 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) act as adaptor proteins linking TNF receptor superfamily members to intracellular signaling pathways, regulating cell death and stress responses. TRAF proteins share a conserved region that mediates interactions with receptors and other TRAF proteins, leading to activation of diverse signaling cascades.
TRAF2 and TRAF3 directly bind to CD40, a receptor involved in B cell immunity, and are critical for NF-κB activation in mouse B lymphocytes. TRAF2 also functions with TRAF6 in CD40 signaling in non-hematopoietic cells and interacts with the lymphotoxin-beta receptor (LTβR) along with TRAF3 and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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